Tag: transporter models

Transporter Models StarDrop integration

Last week we held a webinar organised by our colleagues from Optibrium on “In Silico Transporter Modeling and its Role in Computational Toxicology”, where we presented our new Phenaris Transporter Models StarDrop integration. In this webinar, we outlined computational approaches to predict the transporter interaction profile of compounds in order…
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Webinar Recording: Transporter Models V2

On November 24th, 2020 we held a webinar on the recently released version 2 of our Transporter Models. The webinar was recorded, so you can rewatch if you missed it. With the addition of three new transporter, we are now offering models for 9 transporter (P-glycoprotein, BCRP, BSEP, MRP3, OATP1B1,…
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Transporter Models Version 2 released

Transmembrane Transport Proteins (TMTs) control nutrient uptake, ion transport, and drug transport across biological membranes. Predicting substrate and inhibition profiles of small molecules towards these transporters helps medicinal chemists to prioritize compounds in an early phase of the drug development process and guide toxicologists in the safety assessment of candidate…
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P-glycoprotein (MDR1, ABCB1)

P-glycoprotein (MDR1, ABCB1) – the prototypic polyspecific ABC-transporter When in 1976 Juliano and Ling discovered that the main difference between a wild type tumour cell and a multidrug resistant tumour cell is a glycosylated transmembrane protein which reduces the accumulation of cytotoxic agents in the cell, this marked the beginning…
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Webinar Recording: In Silico Transporter Modeling

If you missed Gerhard’s SaferWorldbyDesign Webinar In silico transporter modeling and its role in computational toxicology, you can now watch the recording here! SaferWorldbyDesign Webinar: In silico transporter modeling and its role in computational toxicology Transmembrane transporters not only play a major role in ADME but they are also increasingly linked to…
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Webinar: In Silico Transporter Modeling

We are very grateful to our colleagues from Edelweiss Connect for giving us the opportunity to present our Transporter Models and its role in computational toxicology in their SaferWorldbyDesign webinar series on April 16th, 2020 at 10 am CEST! SaferWorldbyDesign Webinar: In silico transporter modeling and its role in computational…
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Webinar recording: Computational Toxicology

If you missed Gerhard’s webinar on Computational Toxicology, where he also talked about our products ToxPHACTS and Transporter Models, we have good news for you! The webinar was recorded and you can watch it here. Computational Toxicology – from models to workflows Development of a new drug currently takes 10…
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Demo videos about our products

To give you a closer insight into the functionalities and design of ToxPHACTS and our Transporter Models we produced short demo videos of our products. See how you can easily draw and analyse your compounds and get results in a standardised and aggregated form with state of the art data…
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Launch of Transporter Models

The wait has come to an end – our Transporter Models are officially available for purchase! These computational models can predict ligand-transporter interaction in 3 easy steps: log-in, upload SDF files, run prediction.   We offer 3 competitive pricing models (Academia, SME, Enterprise) and our very first customers get 50%…
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