Webinar on our StarDrop integration
In silico transporter modeling and its role in computational toxicology
Transmembrane transporter not only play a major role in ADME, they are also increasingly linked to toxicity. In this Webinar, our CSO Gerhard Ecker will outline computational approaches to predict the transporter interaction profile of compounds in order to minimize the risk of failures in drug development. Methods presented comprise classical machine learning models as well as deep learning approaches. The latter were also used to overcome insufficient size and imbalancy of toxicity datasets. A combined use of structure-based methods for prediction of molecular initiating events and machine learning led to a model for mitochondrial toxicity. Finally, our Transporter Model Platform and its integration in StarDrop will be shown.
Join our Webinar on 29 April 2021 at 17:00 CEST.